Does your gut feel off most days of the week? Bloating, diarrhea, and farts standing in the way of you accomplishing great things? Keep reading to learn the 5 best gut healing powders for natural GI repair chosen by expert functionally-trained and board-certified dietitian nutritionist Kylene Bogden.

1. MegaMucosa by Microbiome Labs

Forget the fluff. We are jumping right to our #1 gut healing powder of all time, MegaMucosa by Microbiome Labs.

As a dietitian for almost 15 years now, I have seen the most success with MegaMucosa.

This bad boy is the first of its kind to provide comprehensive gastrointestinal mucosal support.

Not only is this formulation magical, but Microbiome Labs, the maker of MegaMucosa ONLY specializes in gut issues. This is not a company that promotes 50 products for 50 different ailments. 

So, there are two things you need to know: 

#1 What is in this product?

#2 How to take it.

What is inside MegaMucosa?

MegaMucosa contains:

  • Four major amino acids
  • Three powerful, dairy-free immunoglobulins
  • Bovine Serum Albumin
  • Citrus Bioflavonoids

This specific blend is crucial for supporting intestinal mucosa. Intestinal mucosa is so important to our immune system because it contains 150x more surface area than our skin!! As a result, the mucosal system is responsible for so much of our body’s immune system function. When our mucosal lining has worn away, we become symptomatic, and overall health gradually begins to decline. 

Another reason why this is at our #1 spot? The formula is simpler than most, thus allowing the vast majority of individuals to experience great tolerance.

How do you take MegaMucosa?

MegaMucosa comes in capsules and powder. While both options are great, I tend to see better tolerance with the powder. I’ve also found that effectiveness increases when the powder is taken on an empty stomach.

When taking the MegaMucosa powder, mix one scoop daily with water. You may take it with or without a meal.

If you decide to embark on the capsule route, start with 3 capsules daily, with or without a meal for one week. If well tolerated, increase to 6 capsules daily with or without a meal.

MegaMucosa is not recommended for children under 3 years of age.

👉🏻Be sure to check it out on Fullscript where you will pay $14  less PER BOTTLE💰✅ than companies like Amazon that sell the same product!

2. GI Revive by Designs for Health

Our second runner-up is GI Revive by Designs for Health. This is another fan favorite, not necessarily for the taste but for how clients feel. Many report relief within one week. 

GI Revive is incredible at calming the gastrointestinal lining. Its main purpose is to strengthen the lining enough to be permeable for nutrients to enter but not “leaky” enough to allow toxins, harmful microbes, and allergens to float through.

What: A unique blend of amino acids, minerals, and botanical extracts. The star lineup features marshmallow root, DGL, l-glutamine, slippery elm, and aloe vera extract. 

How: Mix one scoop of GI Revive powder in 8 ounces of water each day unless otherwise directed by your dietitian. 

👉🏻Check it out on Fullscript for a discount that is $16 less PER container than most websites! 

3. Enteromend by Thorne

Can of Enteromend by Thorne, one of the best gut healing powders.

Enteromend by Thorne is a delicious vanilla-orange gut healing powder designed to calm and repair the gut. We love Enteromend because it is one of the most comprehensive formulations on the market and its ingredients come in easily absorbable forms. Enteromend is honestly a tie for second place. We often have clients try both to see what they prefer.

Picky palette? Go for Enteromend. 

What: Enteromend includes a highly absorbable form of curcumin to calm inflammation, sun fiber to fuel healthy gut bacteria, l-glutamine to repair the lining, and aloe to resolve stomach upset.

How: Mix 1 scoop with at least 5-6 ounces of water one to two times daily or as recommended by your dietitian.

👉🏻Check it out on Fullscript for a discount that is $19 less per container💰✅ than other sites.

4. GI Repair by Vital Nutrient 

Can of GI Repair gut healing powder from Vital Nutrient

GI Repair by Vital Nutrient is a simpler version of GI Revive. It contains core gut-healing botanical extracts in addition to zinc and a few amino acids. Some prefer this powder over others as xylitol is the sweetener instead of Stevia.

What: A powder that strengthens the digestive tract lining. It also supports bloating relief and soothes the mucosal layer of the intestinal tract. 

How: Mix one teaspoon in the beverage of your choice 3x daily or as directed by your dietitian.

👉🏻Check it out on Fullscript for a discount that is $10 less per container than other sites.

5. Glutamine Forte by Integrative Therapeutics 

Can of Glutamine Forte GI healing powder from Integrative Therapeutics.

Looking for the simplest of simple gut healing powders just to get your toes wet?

Check out Glutamine Forte by Integrative Therapeutics. This formulation is basic yet powerful. It is also the #1 formula I recommend for athletes who often deal with slight gut issues as a result of training.

What: Each scoop contains 5g glutamine and 100 mg of highly bioavailable curcumin. This formulation is specifically great for targeting muscle and gut inflammation post-workout.

How: Mix with water and take 1-3 scoops daily on an empty. I suggest starting with one scoop and working your way up to 2-3 as tolerated. 

👉🏻Check it out on Fullscript for a discount that is $11 less per container💰✅ than Amazon!!

What Do Gut Healing Powders Do?

Before we dive deep into gut powders, I’d like to address something first.

In an ideal situation, when you’ve experienced chronic gut issues, you would begin working with a dietitian specializing in gut issues and functional nutrition. Your dietitian would start by working through a food and symptom journal. Next, your personal dietitian would likely progress to an advanced stool test in order to gain a more accurate and intricate picture of what is going on inside your intestines. An individualized plan is then created to fix the imbalances.

However, this is not possible for some individuals, and fast, affordable relief is a must.

This is where gut healing powders come into play.

Depending on the specific formulation, gut healing powders can:

  • Assist in rebuilding the GI mucosal layer
  • Seal a leaky gut
  • Grow “good” bacteria
  • Crowd out “bad” bacteria and yeast
  • Improve the gut, and body’s overall immune response
  • Support digestion
  • Enhance detoxification
  • Improve mood
  • Less severe menstrual symptoms
  • Calm any pain/swelling/irritation in the intestinal tract
  • Sometimes even improves post-workout recovery

What Conditions Need Gut Healing Powders Most?

You will likely benefit from a gut healing powder most if:

  • You have numerous food sensitivities and or allergies
  • You experience chronic bloating and or gas
  • Your gut/gut lining constantly feels inflamed
  • You struggle to digest basic foods
  • You have one or more autoimmune conditions
  • You are chronically ill – constantly catching colds or cases of flu
  • Your injuries take longer than expected to heal
  • You experience any form of chronic pain or inflammation
  • Your stool habits are irregular (constipation, diarrhea, strange shapes, floating or oily, trouble releasing, etc.)

Do Gut Healing Powders Improve Digestion?

Depending on what type of imbalances exist in your gut, gut healing powders can absolutely improve digestion.

Ingredients like amino acids, immunoglobulins, slippery elm, glutamine, and curcumin can help your body more effectively detox, assimilate nutrients, repair your gut’s mucosal barrier, and calm the gastrointestinal lining.


In summary, roughly 77% of the human immune system lives in our gut, and a gut healing powder has the potential to completely transform your gastrointestinal health.

However, eating a gut-friendly diet of colorful whole foods, fermented foods, magical prebiotics, and probiotics will never take the place of any supplement. 

BUT, combining the two, and even sometimes starting with a gut-healing powder, can actually be what opens the gates to be able to better tolerate more gut-friendly foods

Whether you are dealing with fatigue, bloating, or food sensitivities, a professional-grade gut healing powder is a smart start.

Now of course, the dream situation would be to discover the root of your gut issues by meeting with a functional dietitian specializing in gastrointestinal disturbances, but when this is not possible, a gut healing powder is the best first step.

Be sure to try one of the powders listed above and see for yourself!